Series: Biology of Extracellular Matrix №10

Title: Extracellular Matrix Biomineralization of Dental Tissue Structures Edition: 1st ed.

Author(s): Michel Goldberg,Pamela Den Besten (eds.)

Publisher: Springer

Year: 2021

Pages: VIII, 305

ISBN: 9783030762827; 3030762823; 9783030762834; 3030762831

DOI: 10.1007/978-3-030-76283-4

DOI owner: Springer-Verlag


Biomaterials; Biomedicine; Biomedicine, general; Chemistry/Food Science, general; Dentistry; Physiology


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Edition ID: 139705005

Added: 2021-10-17 04:00:57

Modified: 2022-04-09 09:49:19

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This book addresses the structural and biological properties of dental and peridental tissue structures and covers their mineralization process. The book contains a description of dentines, cementum, enamel and bone, including collagens, as well as non-collagenous proteins (SIBLINGs, SLRPs, GAGs, PGs, lipids, and MMPs).
The mechanisms of mineralization are described in detail and the book is focused on matrix vesicles, collagen mineralization and the role of non-collagenous extracellular matrix components either as promoters or inhibitors of mineralization. In addition, the matrix components (non-collagenous) of enamel (amelogenin, ameloblastin, enamelin, MMP4, MMP20 and other proteases) are reviewed and their respective roles in dental tissues biomineralizations and tissue turnover are discussed. Additionally, environmental factors involved in enamel / dentin defects are adressed.
With state-of-the-art contributions from experts in the respective domains, the book is
a useful introduction to the field for junior scientists, interested in dental and peridental tissue biomineralization. It is also an interesting read for advanced scientists and clinicians working in dental research, giving them a broader view of the topic beyond their area of specialization.
The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.

Front Matter ....Pages i-viii
Front Matter ....Pages 1-1
Structure of Collagen-Derived Mineralized Tissues (Dentin, Cementum, and Bone) and Non-collagenous Extra Cellular Matrix of Enamel (Yukiko Nakano, Pamela DenBesten, Michel Goldberg)....Pages 3-34
Extracellular Matrix Proteins: Nomenclature and Functions in Biomineralization (Michel Goldberg, Pamela DenBesten, Yukiko Nakano)....Pages 35-51
Front Matter ....Pages 53-53
Collagenous Mineralized Tissues: Composition, Structure, and Biomineralization (Elia Beniash)....Pages 55-74
Non-collagenous ECM Matrix Components Growth Factors and Cytokines Involved in Matrix Mineralization (Annette Merkel, Elizabeth Guirado, Karthikeyan Narayanan, Amudha Ganapathy, Anne George)....Pages 75-108
Odontoblast Processes: New Insights into Its Role in Dentin Mineralization (Yan Jing, Chaoyuan Li, Jian Q. Feng)....Pages 109-123
Small Leucine-Rich Proteoglycans (SLRPs) and Biomineralization (Yoshiyuki Mochida,
Patricia Miguez, Mitsuo Yamauchi)....Pages 125-155
Cementum Proteins Beyond Cementum (Higinio Arzate, Margarita Zeichner-David)....Pages 157-217
Biochemistry of Non-collagenous Proteins of Bone (Jeffrey P. Gorski)....Pages 219-240
Front Matter ....Pages 241-241
Human Tooth Enamel, a Sophisticated Material (E. F. Brès, J. Reyes-Gasga, J. Hemmerlé)....Pages 243-259
Proteinases in Enamel Development (Shifa Shahid, John D. Bartlett)....Pages 261-270
Enamel Matrix Biomineralization: The Role of pH Cycling (Wu Li, Yan Zhang, Sylvie Babajko, Pamela Den Besten)....Pages 271-293
Environmental Factors and Enamel/Dentin Defects (Sylvie Babajko, Pamela Den Besten)....Pages 295-305
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